Last edited by Feran
Monday, May 11, 2020 | History

5 edition of Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy found in the catalog.

Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy

by C. JULIAN, ED ROSENTHAL

  • 73 Want to read
  • 30 Currently reading

Published by Springer .
Written in English

    Subjects:
  • Applications of Computing,
  • Chemistry,
  • Chemotherapy,
  • Radiotherapy,
  • Medical / Nursing,
  • Medical,
  • Chemistry - General,
  • Oncology,
  • Science / Chemistry / General,
  • Adjuvant treatment,
  • Antineoplastic agents,
  • Cancer,
  • Congresses

  • The Physical Object
    FormatHardcover
    Number of Pages262
    ID Numbers
    Open LibraryOL10323709M
    ISBN 100306422603
    ISBN 109780306422607

    Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst. ; 91(24) (70 mg/m(2) per day) and 5-fluorouracil ( mg/m(2) per day) by continuous infusion. The two arms were equally balanced with regard to age, sex, stage, performance. All patients received an initial nine-week cycle of systemic chemotherapy, followed by radiation therapy and concomitant fluorouracil treatment, followed in turn by a second cycle of systemic Cited by:

    Roberts WS, Kavanagh JJ, Greenberg H, et al. Concomitant radiation therapy and chemotherapy in the treatment of advanced squamous carcinoma of the lower female genital tract. Gynecol Oncol Cited by:   Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. It is not yet known if combination chemotherapy is more effective with or without hypofractionated radiation therapy before surgery in treating patients with pancreatic cancer.

    William E. Jones, Charles R. Thomas, Joseph M. Herman, May Abdel-Wahab, Nilofer Azad, William Blackstock, Prajnan Das, Karyn A. Goodman, Theodore S. Hong, Salma K. Subsequent clinico-pharmacologic investigations led to the realization that only prolonged continuous infusions combined with appropriately fractionated, cyclical radiation therapy would maximize the clinical utility of this approach. Infused FUra radiation-sensitization therapy reaches its maximum efficacy against the squamous-transitional Cited by:


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Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy by C. JULIAN, ED ROSENTHAL Download PDF EPUB FB2

Concomitant Radiation Therapy and Doxorubicin by Continuous Infusion in Advanced Malignancies - a Phase I-II Study - Evidence Of Synergistic Effect in Soft Tissue Sarcomas and Hepatomas C. Julian Rosenthal, Marvin Rotman, Inder Bhutiani.

The Paperback of the Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy by C. Julian Rosenthal, Marvin Rotman | Due to COVID, orders may be delayed. Thank you for your patience. Book Annex Membership Educators Gift Cards Stores & Events Help. This book presents information on the following topics: theoretical basis and clinical applications of 5-FU as a radiosensitizer; treatment of hepatic metastases from gastro intestingal primaries with split course radiation therapy; combined modality therapy with 5-FU, Mitomycin-C and radiation therapy for sqamous cell cancers; treatment of bladder carcinoma with concomitant infusion chemotherapy and irradiation; a treatment of invasiv bladder cancer by the XRT/5FU protocol; concomitant.

The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer.

This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation.

Section II Antineoplastic Effects of Radiation Therapy and Concomitant Chemotherapy by Continuous Infusion.- A. Principles and Therapeutic Applications.- Theoretical Basis and Clinical Applications of 5-Fluorouracil as a Radiosensitizer Concomitant Radiation Therapy and Doxorubicin by Continuous Infusion in Advanced Malignancies - A Phase I-II Study - Evidence of Synergistic Effect in Soft Tissue Sarcomas and Hepatomas.- Cis Platin by Continuous Infusion with Concurrent Radiation Therapy in Malignant Tumors (A Phase I-II Study) Discount prices on books by Marvin Rosenthal, including titles like Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy.

Click here for the lowest price. Carcinoma of anus, Chemo-radiation therapy, 5-fluorouracil, 5FU, Mitomycin C, COncomitant infusion, Local control and survival, Clinical results, Hybrid spheroid assay.

Previous article in issue Next article in issueCited by: This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation.

Thus. A continuous infusion of 6 mg/m 2 daily was administered using an autonomous chemotherapy delivery device (Deltec; Paris, France). Creatinine clearance was calculated every week during concomitant chemotherapy-radiotherapy and cisplatin delivery was stopped when clearance was equal to 60 mL/min or below this value.

Postprogram TherapyCited by: Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.

Deenen MJ, Dewit L, Boot H, Beijnen JH, Schellens JH, Cats A. Int J Radiat Oncol Biol Phys, 85(5):e, 01 Apr With the development of reliable drug pumps and safe long-term venous access catheters, the continuous infusion of chemotherapeutic agents has become clinically feasible.

The available studies on infusion therapy with 37 antineoplastic drugs are analyzed. With the majority of agents, infusion studies have either not been performed or the completed studies have failed to demonstrate improved Cited by: Chemotherapy consisted of 5‐FU, mg/m 2 continuous infusion from day 1 to day 5 and days 29‐33 and mitomycin C, 15 mg/m 2 on day 1.

No chemotherapy was given during the boost. The addition of concomitant 5‐FU‐mitomycin C chemotherapy to full‐dose radiotherapy resulted in an increase of local by:   Chemotherapy consisted of continuous infusion fluorouracil (5-FU) at mg/m 2 /d for 5 consecutive days (days 1 to 5) and hydroxyurea (HU) at 1 g orally every 12 hours for 13 doses starting the evening before the start of irradiation.

Radiation therapy was given as single to Gy fractions for 5 consecutive days (days 1 to 5) with Cited by:   The purpose of this overview is to describe the available evidence on the effects of radiation on ambulatory infusion pumps used to deliver chemotherapy, heighten awareness of this issue within the clinical community, provide considerations for minimizing possible negative effects on patient care, and encourage the monitoring of infusion Cited by: 2.

concomitant use of chemotherapy and radiation, are the more impactful; however, si nce several pa tient-speci fic risk fact ors are poten tially modifiable through preventative actions (e.g., poor.

Author(s): Rosenthal,C Julian; Rotman,Marvin,; Conference on Continuous Infusion Chemotherapy and Its Interactions with Radiation in the Treatment of Malignant Tumors,(1st: New York, N.Y.) Title(s): Clinical applications of continuous infusion chemotherapy and concomitant radiation therapy/ edited by C.

Julian Rosenthal and Marvin Rotman. Continuous infusion chemotherapy as a radiation-enhancing agent for yttriumradiolabeled monoclonal antibody therapy of a human tumor xenograft Steven W.

Remmenga, David Colcher, Otto Gansow, C. Greg Pippen, Andrew RaubitschekCited by: Chemotherapy for-cancer is in a state of evolution. Because some cancers can now be cured with chemotherapy as a singular modality, this therapy can no longer be viewed as simply a palliative contribution.

Chemotherapy has assumed an important role as an adjuvant to other modalities, including both surgery and radiation therapy. For some tumors, the primary application of chemotherapy in a. Douple EB, Wills ML, Jones EL: Radiopotentiation in a murine tumor (MTG-B) by continuous infusion platinum.

In Clinical Application of Concomitant Infusion Chemotherapy and RT, Rosenthal C J and Rotman M, (eds.), Springer-Verlag, New York, 96, 7. Jones EL, Douple EB: Hyperthermia and low dose rate irradiation.

Treatment consisted of preoperative external beam pelvic radiation therapy (EBRT) and concomitant chemotherapy (CT) during the first and fourth weeks of radiation combining 5-fluorouracil and cisplatin.

The pelvic radiation dose was Gy over weeks. – Chemotherapy + radiotherapy administered at full or nearly full dosage (split course radiotherapy). – single agent chemo with continuous course of radiation – alternating chemo with radiotherapy • Drugs used: – Cisplatin ( mg/m2 every 3 weeks for 3 doses) – Carboplatin (45 mg/m2 for 5 days during weeks 1,3,5 & 7) In Part 4, the effect of continuous ASP exposure during consolidation will be evaluated.

During remission induction, subjects will receive a 7+3 induction regimen consisting of daunorubicin on days 1 through 3 and cytarabine as a continuous infusion on days 1 through 7.